Jennifer Gierisch, PhD, to Run Duke Trial Site for New Weight Loss Study

In partnership with the University of Wisconsin School of Medicine and Public Health (Clinical Coordinating Site PI: Dr. Corrine Voils), Duke received $2.7 million award from the National Heart, Lung, and Blood Institute (NHLBI) to serve as one of 2 clinical sites for Log2Lose, a study to examine whether incentivizing weekly weight loss and dietary self-monitoring will help participants achieve and maintain clinically significant weight loss. The Duke trial site will be led by Dr. Jennifer Gierisch, Associate Professor in the Department of Population Health Sciences in the School of Medicine and run by Megan Oakes, Senior Research Program Leader; Shauna Malone, Senior Clinical Research Specialist; and Jamiyla Bolton, Senior Research Program Leader at the Duke Global Health Institute. 

Additionally, Duke University received a separate $2,014,796 award to be the Data Coordinating Center (DCC) for this multi-site trial, led by PIs Dr. Ryan Shaw and Dr. Jane Pendergast. The DCC will assume responsibility for managing the technology needs of the study and for collection, analyses, and reporting of the data. Dr. Shaw is an Associate Professor and Digital Health Scientist in the School of Nursing and Dr. Pendergast is a Professor in the Department of Biostatistics & Bioinformatics in the School of Medicine. 

In this two-site, randomized, single-blinded, longitudinal 2x2 factorial study, adults with obesity from Madison, WI and Durham, NC will be offered an 18-month, evidence-based behavioral weight management program comprising an incentivized weight loss intervention for 6 months (Phase I), an incentivized weight loss maintenance intervention for 6 months (Phase II), and a non-incentivized weight maintenance intervention for 6 months (Phase III). Log2Lose is designed to be scalable by using available technology and automating the process of analyzing data to provide incentives in near real-time. If successful, the intervention could be paired with various weight loss interventions offered by clinicians or payers or integrated into a variety of patient and consumer-facing technologies.