Lesley Curtis, PhD

Chair, Population Health Sciences
Lesley Curtis, PhD
Director, Center for Pragmatic Health Systems Research, Duke Clinical Research Institute
Professor in Medicine, Duke University School of Medicine

A health services researcher by training, Dr. Lesley Curtis oversees a portfolio of projects that use observational data to address questions related to clinical and comparative effectiveness, pharmacoepidemiology, health care delivery, and epidemiological trends across a broad array of clinical conditions and clinical care settings.

An expert in the use of Medicare claims data for health services and clinical outcomes research, Dr. Curtis has led the linkage of Medicare claims with several large clinical registries and epidemiological cohort studies including the Framingham Heart Study and the Cardiovascular Health Study.

Dr. Curtis serves on the American Heart Association/American College of Cardiology Task Force on Practice Guidelines and on the American Heart Association’s Task Force on Performance Measures, working to continuously improve the incorporation of evidence into health care delivery. Additionally, she serves as Co-Lead of the Data Core for the FDA’s Sentinel Initiative, Co-PI of the NIH Health Care Systems Collaboratory, and Co-Lead of the Distributed Research Network Operations Center for PCORI’s National Clinical Research Network (PCORnet), working with health systems and patient networks to develop a harmonized data infrastructure for robust observational and interventional research.

Dr. Curtis received her B.A. in Economics at Washington University. She received an M.S. in Public Policy Analysis and her Ph.D. in Health Services Research and Policy, both from the University of Rochester.